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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cfce92c2c50e942e7f632b1dc176d8a8998d2729508eb236d40dcf5f5ab60c7' 
  AND token = 'eBMagSA+JnrZvdE1xoXLE8LSi9bATJx75ykLk290jZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}