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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1a2ca1c40ac44ea357c606d960a778c02b340741b9c5b5479f8ebe383975886' 
  AND token = '2+a/a+QCJuCIz3uMUCcvFu5FjKTmW80Y7+GeeFL81zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}