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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35a8cbf126e9778d5d14de6fb4bf165dfd86fc6999ee796abc57f1b6d51f9e96' 
  AND token = 'qztn0z1+feU/tVYC376yGL849Hc4ZSNGkMowhtTkRvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}