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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27e34dc856f07ca3d5f1cedbd5643a964bbe4d690d57551d274dda20d3fc64c8' 
  AND token = 'Wr5sNJ2Rfki7w72SeqmNia8C//3xInkqZtKuwW1NUqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}