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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '102f2a9f66ebfe4278bb1144124ad865e2db3c8ecbbdd6adfa1e27bec501f972' 
  AND token = 'pfuZGt8L7kkMA0JaIKIsytEUrVcSk57QOWXhXj33d5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}