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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980cb6225d340ff639e81551d63c74817464c7f23aedfed0a7458464fff2f27c' 
  AND token = 'NThL25KCB9mBfyFioxcCvocQ99twW5PPhi+D8tJ7rx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}