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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '887e0eec4c64c59f2f1ca6af2a6c6e36b1b3d6b4815edd415fc45d350879cfc8' 
  AND token = 'IFqkyS9SkHcpaXmNBiwPcRALyIi6mv3zz3PPrGV2bVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}