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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca9428e1ad1a63471cfdc3fd623ff2897a7aef46b548f9482c1d43d42c50bde' 
  AND token = 'DhDNSjG5yx+a8mX3qbsh2kWQzPBte77klMaGCdUNRK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}