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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae46dd7b0bc4e2b0c063c5edaa841e0302e435be30d01a7f5ae04e04b6ea12b' 
  AND token = 'ZY8E6usrR2oVnuRLr7IRMbP9NF+z6SYPALCpHGw+yT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}