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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d7257c9c82318fd776215783d56c8b405368a7a60194d74035866026774a56' 
  AND token = 'Azv0W35ZRr7JEue1ZNhEM5d0ZSMGXRJI12CvGDdn5sk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}