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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce04c3136d9532c5904222e47d5b42ef1821bd049b53ba0723a4a240c485366' 
  AND token = 'w+ZD8qiK58E9ty4lmKWtpK3xilwJuba6G69Mjcr8R/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}