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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae80986dfa8e65f69ce741e2f6b64c240f9a165244a383fa5b2ebb08955b3c70' 
  AND token = 'ZXAV0xIm16vuzdzDz96Q0M7fuBhu2oOHe+EEdeALvRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}