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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c8d4122880711eb3287c5657800b84f676b40004fa5c4d4bd95ece6db6c8ac0' 
  AND token = 'jGvpy4lOMDMaF4J45mFT9OJ8qD0PE+OOh/TLnTVq7ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}