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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d3ffc26fa4e06814e8d3e1c295aafc2e08f93e32c5f8b9cf86d5201bcde3a03' 
  AND token = '1MpUGRloY4k4bSM0wskdQN/6URKXDrMsibBaI/1Vumo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}