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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1b391767086f51e25fe36be1989f27a03796e188210bc3784b3028fd5c227c' 
  AND token = 'ND7m8LKBiGM5MMTUB+xI9fCLY0X83RdaQpVGDMn8Jks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}