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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a3d781bd4a0b5a857ca0454e19850378a3004f27ce40a8a735f3883b883e057' 
  AND token = '1FFIIlhj+eHx0IA9nZtZMLdSHLSb8WWuhjv0/v4KE3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}