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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '612eaa0dac3a121f45faea8a78680b86801e48ed5da073f80d62c37b7d0f2701' 
  AND token = 'eM/mRJ15qT/dMqJhi5vZ4JIDF3OaaEsUBeMl+W7OBhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}