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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bebc5e215d8a154cda146ba73af5552063c8e1facf4f718dc86d55632285f17' 
  AND token = '+MLusg65z1SvUS5XhT0xAoKerJ8aR32GvAX3PHqzEC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}