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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41d9d75d385fbb95e02fbb7fca03eeb3bda36ce75cadb9c37c777c158a23af51' 
  AND token = 'kPolOtBIhelb4xWFHq7BhENd/peBdzNF52K4cfSTW5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}