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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e85aefb2427ae41ff9af5bd3922c46155a319905a39c3c63025afbb3a081d8a' 
  AND token = 'NB7If0s18yfoThTFL7QOO3gjB1cTSM01DJ49tJlJwsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}