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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21f18d34ec9fe5d705962e15c2b687a7a2f7cce3ba6fe0f88673c1882dd715da' 
  AND token = 'l08HkJMXe3qLg7Ebw0hgC2LfnlZm9rXFU0okSUx1qmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}