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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8afd0378c605f16875b1eb205aa460dbe0a42153abd1c3518e8866961a9509' 
  AND token = 'D9C9KbZ/Ke7vCUhiS0QUbZxJ7qbkDF8yxwUJYgulhh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}