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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac83156f88c87d06fea4ee07d33f1f0ebb2dbfa0268191c4c8580c36278d5652' 
  AND token = '2X984NeoqWI3puc+5jd15kC6PIDK2ktk+ejZwZyMhUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}