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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '751c15afa4db7fd00e9b80d0611acc3ce896b4c2646f047b85608157aa3ee899' 
  AND token = 'HRuCMhct5TLg+H9u3fSHt9vkQxD87g3pDGJ6DllMIX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}