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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7895b2bebe98d36f998cac31c5c3a7b0749a0ca10e985602f1db51357d5dc6fd' 
  AND token = '6VHHf8ktpDIEnH0j5RJV/achwTUIfpKwPjnDo5EO+R4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}