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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80605d330f624a2748c2797927dbf800c92e0692a9c6cf43e622db39218c3300' 
  AND token = 'joTlmVtb/XWSOsxGFYeCuCxU44UyT+YdRVzUJAS6YYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}