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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3846a8aa961a5bce85fdbadea841538cd058ae71f0ca522006e246afd7cb940e' 
  AND token = 'ZbdGWjV/2g7yTfOS/djqYTH0MMp/XH64QRi9DVvGMAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}