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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6889cc4e8e384698a6fd5db2c70eb465fd684d98e2d21353b9cd048570ff5e70' 
  AND token = 'qyYkIhENDB+t+bSQYeuGJiqYJJsDB+zHLq5f2TmI72I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}