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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8eb2e32fc7e0333977a58d652f29837fb5e6ce54cd19c87de377fbe101c1c1' 
  AND token = 'b+2+55mqYScc0GJh92ncQcxgGzWjOqMmYxRJMrB+6Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}