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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d8a9d5c9834210de833b71dc739809620bcb924b31e6644a01e9e8aca620661' 
  AND token = 'NpdKOToHdpXQywUDXu4s9iHkWC0jdFAbmJxla1pCB+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}