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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43693dc02dda3ccba08d24b7d084a361b3dea4bb31bc3a0b5ad818e4871e8b80' 
  AND token = 'y6gAlur08k6+yKK6bwCaEmeC1mcVz4gLZqPo5YqWCh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}