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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdeb065af3b4e5b2c881475a690702a3110275fc9d7497099b08d92f970cf12b' 
  AND token = '3O0NWsVM0Pljv5xG/tLWwYUwJIPFgoWEid27R99Zsuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}