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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a3b0b9584dcb4400aba332448ada8251a8c3dbb251d7159ff057cfe6457509' 
  AND token = 'Z+p4VVSbQNHPtgXt7m2q2+EAx0gpZhsKgj/baoVGEiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}