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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71564ab09ffd4eda6eda360e30e00044dbca40e18695af79c08cbac67ea527f3' 
  AND token = 'PYrs2TOPBj6qHdk3YXx2l1Wv/co4P0zHpV19OgtfQQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}