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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d61f017f6aed298303ba4e31998e273c34e7b29b452da86cda780aedeff364e' 
  AND token = 'aTbuW4k06oZhMsbeR6j6191eL4phTAeiQYhJkq1f+PY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}