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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55c1179319f27d58973c130775292f9330f25e66fe1718e31867992488987347' 
  AND token = 'vVcimJKahKuzy/VK+rZovuXSiQyI4O/rPFvSe32HvFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}