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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8923f44f0eb2bbdf542b06029ab273358fb4f229a6662d05015b8da01b5794c' 
  AND token = 'RrUw6PcInXtsHQla7H8HLoWr2idaSZ6WHgwTuUc9+o8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}