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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e9916eb6a644cfc90dac08797f0fe5f550077f7315f3950a68ba45412beddee' 
  AND token = 'wUVLUNNRyB4KcWPpH/dz6m5DKyT2xCx1PJDCnwcA9Vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}