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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51cc7fcfdf9d79e103a72f938e61063dd877d870fd1b46625a685e1509d7ab2c' 
  AND token = 'aEw4pVb/o9hyLsgUDXSuHz3mM55UQNmteZSsMkxiZ1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}