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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57c6ea2e0a1fb10390be57603640c55e08489fcb7acb0dd2564420e0803b1497' 
  AND token = 'xa2FrQjWYWreD6A05h2mt/jRMe1d7/hTlm65hSE7i/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}