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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd486ff65efea1959090740c0093423592e2e6171ab8d03374d962a83292e51be' 
  AND token = 'R1FU2o89Rlq7LLmGfey3u2iJLl78nd2wDSZmP4M/03M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}