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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ef6f151ab474e204c9b1a4464209493737d961eeb9fbb2a6c5729d39c5a947' 
  AND token = 'TUp+83sDrezMiAIRmKs1/kCF5Hv22TzP/fLhRNhUJi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}