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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eff84aea5d4522eed0d8b6d9704d70f03a931d6578881427151d64ef2f7f5b0' 
  AND token = '8e3/SmV/1FqUZ1tdYMHgos5+EiIJ6klEMbGSYuNhw6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}