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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f8af7258081f7c597d7c546e5be77c546b0c83760c900fa00eab2602eb2d065' 
  AND token = 'tFQQAmp3U11aStNr5WpeOxjGGhr1jVBhnanOus/RH0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}