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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88f5b63ffa22b174870e95b95bf048af48dd76d3fe1026969a4e2d8733490570' 
  AND token = 'QGn75owM6f25xigMPB/prS7jgw4NXvmQxN7llYPdXA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}