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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd41eaf1cd154f79f977835672eed9a219af1b644281b43cd206e3c48fb3439ab' 
  AND token = 'SzKxvmvsMeLX0hZPLgB44c0I9GRbi1fATVqEaZuaelE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}