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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bef76f9d393673d95d58f21ccb4de151e06ac2a247a4c7b3f16ac7ed7a6323a' 
  AND token = 'C5mEiyNr+VLX1UbxZhg6fGfIbC1sP++s1Hxi3uEIKTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}