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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7ef686ee62a8dfd39db9325f69345b01829bb2933206388239bee292205fdb2' 
  AND token = 'oMu1r7RFYsPvRzxT9DXlGhQ8QOlwqTTF3Bhe+ZClvPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}