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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe378a67924499cf6e6c5396b8b8f689b2f0f3533aa88720abb873793d3b7b8b' 
  AND token = 'y1BaclY6QOl8l0A3Uuaxe0pzbB9Sr1WmC/9rRDpDT0s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}