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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfe2a26de9629895dba3e6e24c13267a57ed152b6a33b6a114cda995e7729f20' 
  AND token = 'q8UpWS6adTRUZlJSiqrTCYTeTagdw6BdM4voffLVGlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}